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NFL Week 6 Player Prop Research (2026): Matchups, Injuries & Anytime TD Markets

Looking for the best NFL player props in Week 6? We won't hand you a list. What's here is the research: matchup notes for the 13 games still to play, the injuries to watch, red-zone usage for anytime TD markets, and how prices differ from book to book. Think of it as the homework behind the best NFL prop bets for Week 6, minus the answer key.

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Week 6 NFL player prop bets at a glance

Fourteen games, four teams on bye (Bengals, Lions, Dolphins, Vikings), and one game that starts before most of America has had coffee.

The Sunday 1 PM ET window is 7 games (G3–G9), and the Desk's research for them is at centerpointsports.com before kickoff. London kicks off at 9:30 AM ET (2:30 PM BST), so it sits this one out.

Anytime touchdown scorer Week 6 board: red-zone usage, not picks

Start with who actually gets the ball near the goal line. Rows run through Week 5, Monday night included (refreshed Tue Oct 13). Anyone ruled out on Friday's report comes off the board.

Red-zone work is one input, not a prediction. Prices for each of these markets vary by book; compare them in the Line Shop before you decide anything. No pick is guaranteed.

How to read the game notes: "pass/rush yds allowed" is per game, "net yds/dropback" counts sacks, and ranks run 1st = most allowed. Every number comes from nflverse play-by-play 2026 (CC-BY 4.0), aggregated by the Desk (data last modified Tue Oct 13, 2026, 8:55 AM ET; 79 games through Week 5, Monday night included). Injury lines come from the Week 6 official injury reports plus the team sources named; each line shows its check time (latest Fri Oct 16, 8:39 PM ET). For the Sunday games they show the Friday final report with game designations (Out, Doubtful, Questionable); Houston and New Orleans come from NFL.com because their club tables had no Friday column. SEA@DEN (played Thu Oct 15) shows its final report and the official inactives. Washington and San Francisco show practice participation only; their final designations come Sat Oct 17.

NFL player props for the 1 PM games: the Sunday early window

Seven games, one kickoff time, and the slate most people show up for on Sunday morning. Start here.

G3 · Bears @ Falcons · Sun Oct 18, 1:00 PM ET · FOX · Mercedes-Benz Stadium, retractable roof · 1 PM window

Matchup notes

• Chicago leans run: a 51% pass rate (4th-lowest) and about 35.6 rush attempts per game. Red-zone carries are split between D'Andre Swift (21, 10 inside the 5, 4 TDs) and Kyle Monangai (14, 6 inside the 5, 3 TDs).
• Chicago targets: Luther Burden III 35 (22% share), Rome Odunze 29 (273 yds), Kalif Raymond 27.
• Atlanta's defense allows the 4th-fewest rushing yards (82/g), at 4.06 yds/carry. Through the air, it's a different story: the 6th-most passing yards (248.4/g). Still a pass-funnel defense against a run-leaning offense, and that tension is the whole research question.
• Atlanta's offense passes 47% of the time, the lowest rate in the league. Drake London has 36 targets (28% share, 488 yds). Bijan Robinson has 20 red-zone carries (7 inside the 5) and 5 TDs, plus 25 targets. Brian Robinson Jr. has turned 5 red-zone carries into 4 TDs.
• Chicago's defense allows 215.4 passing yds/g (12th-fewest), but 7.58 net yds/dropback (3rd-most) and 4.5 yds/carry (11th-most).

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 8:39 PM ET)

• CHI (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: LB T.J. Edwards (hamstring), LB Keyshaun Elliott (quadriceps), RB Kyle Monangai (thumb/toe), DL Dayo Odeyingbo (quadriceps). Questionable: DB Tyrique Stevenson (hip), DB Kyler Gordon (calf) [FP/FP/FP; designation as posted by the club], QB Caleb Williams (hamstring) [FP/FP/FP; designation as posted by the club]. (chicagobears.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• ATL (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: CB C.J. Henderson (groin). Questionable: DE Za'Darius Smith (neck). No designation: LB Kendal Daniels [–/LP/FP], ILB Divine Deablo [LP/FP/LP], WR Drake London [–/–/LP], QB Michael Penix Jr. [FP/FP/FP], OT Jawaan Taylor [–/DNP/FP], DE Cameron Thomas [–/LP/FP]. (atlantafalcons.com Week 6 final report via the official team-site injury feed; checked Oct 16, 8:39 PM ET).

Prop markets worth researching

• CHI QB passing yards / attempts: Atlanta gives up yards through the air, but Chicago would rather run. The question is whether game script forces its hand.
• CHI receiving yards / receptions (Burden, Odunze, Raymond): same pass-funnel logic, with the targets spread across three receivers.
• CHI RB rushing yards (both directions): Chicago's strength runs straight into Atlanta's strongest unit.
• Bijan Robinson rushing + receiving yards and anytime TD: a red-zone workload against a defense that allows above-average yards per carry (4.5).
• Drake London receptions: a big target share against a defense that limits passing yards but gives up yards per dropback. Volume vs. efficiency.

G4 · Ravens @ Browns · Sun 1:00 PM ET · FOX · Huntington Bank Field, outdoors on the lakefront · 1 PM window

Matchup notes

• Derrick Henry has 28 red-zone carries, 13 inside the 5, and 8 TDs. That's 2nd in the league in red-zone carries, behind Detroit's Jahmyr Gibbs (not on this slate).
• Baltimore targets: Zay Flowers 31 (405 yds), Mark Andrews 30.
• Cleveland has allowed the fewest rushing TDs in our sample (1). It has, however, given up 10 passing TDs. If you're researching a Henry anytime TD, that's the tension.
• Cleveland's offense throws 58% of the time. Targets: KC Concepcion Jr. 29, Denzel Boston 29 (330 yds, 3 TDs), Harold Fannin Jr. 27 (3 TDs). Quinshon Judkins has 9 red-zone carries.
• Baltimore's defense has allowed 6 rushing TDs.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• CLE (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: DT Kalia Davis (quad), QB Dillon Gabriel (back) [FP/FP/FP; designation as posted by the club], DT Mike Hall Jr. (ankle), G Teven Jenkins (back), RB Dylan Sampson (knee). Questionable: DE Derek Barnett (ankle), DT Mason Graham (knee, ankle), RB Quinshon Judkins (ankle), LB Carson Schwesinger (ankle). No designation: WR Denzel Boston (foot) [LP/LP/LP], WR KC Concepcion (concussion) [LP/LP/FP], TE Carsen Ryan (calf) [DNP/LP/FP], WR Tylan Wallace (knee) [LP/LP/FP]. (clevelandbrowns.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• BAL (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: TE Matthew Hibner (hand), QB Lamar Jackson (ankle), C Cam Jurgens (concussion), DL Broderick Washington (ankle). Questionable: G/T Emery Jones Jr. (ankle), WR Ja'Kobi Lane (wrist), G Andrew Vorhees (foot). No designation: TE Mark Andrews (hand) [FP/FP/FP], WR Rashod Bateman (shoulder) [LP/DNP/FP], WR Zay Flowers (toe) [–/LP/LP], S Kyle Hamilton (stinger) [FP/FP/FP], OLB Trey Hendrickson (finger) [FP/FP/FP], CB Marlon Humphrey (hamstring/calf) [LP/FP/FP], TE Nick Vannett (knee) [LP/FP/FP]. (baltimoreravens.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• QB status drives every BAL passing market. Lamar Jackson (ankle) is listed Out on Baltimore's Friday final report (baltimoreravens.com, checked Fri Oct 16, 4:42 PM ET).

Prop markets worth researching

• Henry rushing yards and anytime TD: an elite red-zone share against the defense that has allowed the fewest rushing TDs (1). Something has to give. Or it doesn't, which is also information.
• BAL passing TDs / TE receiving (Andrews): Cleveland has allowed its TDs through the air.
• Judkins rushing yards / anytime TD: Baltimore has allowed 6 rushing TDs.
• CLE TE receptions (Fannin): he earns red-zone targets.

G5 · Titans @ Colts · Sun 1:00 PM ET · FOX · Lucas Oil Stadium, retractable roof · 1 PM window

Matchup notes

• Tennessee WR Carnell Tate has 37 targets, a 26% share, and 274 yds. Wan'Dale Robinson is next with 30. Tony Pollard has 18 red-zone carries (6 inside the 5) and just 1 TD to show for them.
• Indianapolis's defense allows the 5th-most passing yards (254/g) and the 6th-most rushing yards (131.2/g).
• Jonathan Taylor: 20 red-zone carries, 11 inside the 5, 6 TDs. Indy targets: Tyler Warren 36, Josh Downs 34, Keenan Allen 29.
• Tennessee's defense allows 115.6 rush yds/g (16th-most) and 6.98 net yds/dropback (7th-most).

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• TEN (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: S Kevin Winston Jr. (quad), DL Jordan Elliott (personal, not injury related). Questionable: RB Tyjae Spears (knee), CB Joshua Williams (pec). No designation: CB Cordale Flott (chest) [FP/FP/FP], DL John Franklin-Myers (rest, not injury related) [DNP/FP/FP], CB Marcus Harris (ankle) [LP/LP/FP], S Amani Hooker (concussion) [LP/FP/FP], TE David Martin-Robinson (hamstring) [LP/LP/FP], RB Tony Pollard (rest, not injury related) [DNP/FP/FP]. (tennesseetitans.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• IND (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: LB Jaylon Carlies (ribs), WR Ashton Dulin (hamstring). Questionable: TE Will Mallory (thumb). No designation: WR Keenan Allen (rest, not injury related) [DNP/FP/FP], WR Josh Downs (rest/hamstring) [LP/FP/FP], QB Daniel Jones (ankle) [FP/FP/FP], DT Grover Stewart (rest, not injury related) [–/DNP/FP], RB Jonathan Taylor (rest, not injury related) [LP/FP/FP]. NFL.com also lists TE Tyler Warren (groin) Questionable (limited on NFL.com); he is not on colts.com's table (colts.com Week 6 final report, checked Oct 16, 4:42 PM ET; NFL.com Week 6 injury report, checked Oct 16, 8:39 PM ET).

Prop markets worth researching

• Tate receptions / receiving yards: 26% of the targets, against a pass defense that gives up yards.
• Pollard rushing yards: volume against a run defense that allows yards. His red-zone TD conversion has lagged his carries. That's a fact, not a forecast.
• Jonathan Taylor rushing yards and anytime TD: a red-zone workload against a defense that gives up ground yards.
• Tyler Warren receptions: a TE whose target share sits near the top of the team.

G6 · Jets @ Patriots · Sun 1:00 PM ET · CBS · Gillette Stadium, outdoors · 1 PM window

Matchup notes

• Garrett Wilson has 42 targets (30% share, 374 yds).
• Breece Hall (quad) and Adonai Mitchell (finger) are listed Out on the Jets' Friday final report (newyorkjets.com, checked Fri Oct 16, 4:42 PM ET). See Injuries below.
• New England's defense allows the 10th-fewest passing yards (205.4/g) and 91 rush yds/g (6th-fewest).
• Patriots targets: Romeo Doubs 23, DeMario Douglas 22, Mack Hollins 20.
• The Jets' defense is stingy through the air (4th-fewest passing yards, 174.8/g, and the 2nd-fewest net yds/dropback, 4.94) and less so on the ground (119 rush yds/g, 13th-most).

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• NYJ (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: RB Breece Hall (quad), WR Adonai Mitchell (finger), edge Joseph Ossai (ankle), OL Dylan Parham (knee). Questionable: S Dane Belton (knee), WR Omar Cooper Jr. (ankle), TE Kenyon Sadiq (concussion). (newyorkjets.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• NE (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: CB Carlton Davis III (neck), CB Karon Prunty (hamstring). Questionable: WR A.J. Brown (ankle), OT Marcus Bryant (ankle), OT Will Campbell (knee), CB Channing Canada (hamstring), LB Christian Elliss (chest), RB TreVeyon Henderson (ankle), S Craig Woodson (shoulder). No designation: CB Christian Gonzalez (shoulder) [LP/FP/FP], QB Drake Maye (right shoulder) [FP/FP/FP]. (patriots.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• New England's Friday final report lists CBs Carlton Davis III (neck) and Karon Prunty (hamstring) Out, which changes the Wilson research (patriots.com, checked Fri Oct 16, 4:42 PM ET).

Prop markets worth researching

• Wilson receptions / receiving yards: target volume against a stingy pass defense, tied to the NE CB injury status.
• NYJ RB rushing yards: Breece Hall is listed Out on the Friday final report, so check who gets the carries.
• NE RB rushing yards and QB Drake Maye rushing yards: the Jets give up yards on the ground.
• Doubs/Douglas receptions: a spread-out WR tree, with A.J. Brown (Questionable on the Friday final report) the status to check.

G7 · Saints @ Giants · Sun 1:00 PM ET · FOX · MetLife Stadium, outdoors · 1 PM window

Matchup notes

• Only the Rams throw more than New Orleans: 43.6 pass attempts/g (2nd-most) and a 65% pass rate. Chris Olave has 54 targets (28% share, 537 yds). Juwan Johnson has 32 targets, 7 red-zone targets and 3 TDs.
• The Giants' defense has 8 sacks (6th-fewest) and has allowed 9 passing TDs.
• New Orleans's defense allows the 3rd-most rushing yards (150.2/g), 5.14 yds/carry, and the most rushing TDs (10).
• Giants: Isaiah Likely has 48 targets (29% share). Malik Nabers has 46. Cam Skattebo has 11 red-zone carries.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 8:39 PM ET)

• NYG (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: CB Colton Hood (concussion), S Tyler Nubin (neck), TE Theo Johnson (neck). Questionable: OLB Abdul Carter (calf), OL Jermaine Eluemunor (calf), OT Andrew Thomas (groin). No designation: RB Najee Harris (ribs) [FP/FP/FP], WR Charlie Jones (Achilles) [–/FP/FP], TE Isaiah Likely (foot) [FP/FP/FP], WR Darnell Mooney (neck) [LP/FP/FP]. (giants.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• NO (Friday final report via NFL.com; neworleanssaints.com's table still had no Friday column or designations at 8:39 PM ET; NFL.com practice status in brackets for players with no designation): Out: LB Kaden Elliss (calf), LB Anfernee Jennings (knee). Questionable: RB Alvin Kamara (back), WR Chris Olave (illness), DT Nathan Shepherd (illness), CB Lorenzo Styles Jr. (knee), LS Zach Wood (calf) [FP/FP on the club report, full on NFL.com; designation as posted on NFL.com]. No designation: QB Tyler Shough [full] (NFL.com Week 6 injury report; checked Oct 16, 8:39 PM ET).

Prop markets worth researching

• NO pass attempts / completions and Olave receptions: near league-high volume (2nd-most attempts) against a defense with few sacks.
• Juwan Johnson anytime TD / receptions: he earns red-zone targets, and the Giants allow passing TDs.
• Skattebo rushing yards and anytime TD: nobody allows more rushing TDs than the Saints.
• Likely / Nabers receptions: a concentrated target tree.

G8 · Panthers @ Eagles · Sun 1:00 PM ET · CBS · Lincoln Financial Field, outdoors · 1 PM window

Matchup notes

• Carolina is coming off its Week 5 bye. It throws 43.25 times a game (3rd-most) with a 65% pass rate. Tetairoa McMillan has 39 targets (26% share, 385 yds). Chuba Hubbard has 9 red-zone carries and 5 TDs.
• Carolina's defense allows the 2nd-most rushing yards (157/g), the most yards per carry (5.51) and 7 rushing TDs.
• Philadelphia's red-zone touches are thin and spread around: Will Shipley 9, Jalen Hurts 7, Saquon Barkley 5 carries.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• CAR (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: RB AJ Dillon (ankle). Doubtful: OT Monroe Freeling (knee). Questionable: G Damien Lewis (elbow), OLB Jaelan Phillips (hamstring), RB Trevor Etienne (ankle), OT Taylor Moton (lungs/blood clot), DT Tershawn Wharton (neck). No designation: TE Tommy Tremble (ribs) [LP/LP/FP], TE Darren Waller (toe) [LP/LP/FP], WR Jalen Coker (quadriceps) [FP/FP/FP], QB Bryce Young (knee) [FP/FP/FP]. (panthers.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• PHI (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: RB Saquon Barkley (hamstring), DB Michael Carter II (abdomen), OLB Jalyx Hunt (knee/ankle), QB Jalen Hurts (calf), RB Will Shipley (foot). Doubtful: OLB A.J. Epenesa (back). Questionable: CB Jakorian Bennett (knee), TE Grant Calcaterra (back), G Landon Dickerson (knee), C/G Drew Kendall (knee), TE Eli Stowers (quad). No designation: WR Marquise Brown (ankle) [LP/LP/FP], TE E.J. Jenkins (toe) [LP/LP/FP], WR DeVonta Smith (hamstring/toe) [DNP/LP/FP], WR Dontayvion Wicks (hamstring) [LP/DNP/FP]. (philadelphiaeagles.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).

Prop markets worth researching

• PHI RB rushing yards and anytime TD: the softest run defense by yards per carry. Saquon Barkley and Will Shipley are both listed Out on the Friday final report, so check who gets the work.
• PHI QB rushing: Jalen Hurts (calf) is listed Out on the Friday final report, so check who starts at QB before researching QB rushing or anytime TD markets.
• PHI WR receiving yards: DeVonta Smith has no game designation on the Friday final report (DNP/limited/full), and the QB change matters here too.
• McMillan receptions / receiving yards: a high-volume pass offense.
• Hubbard anytime TD: Carolina's red-zone conversion leader.

G9 · Steelers @ Buccaneers · Sun 1:00 PM ET · CBS · Raymond James Stadium, outdoors · 1 PM window

Matchup notes

• Baker Mayfield (right thumb) is listed Out on Tampa Bay's Friday final report (buccaneers.com, checked Fri Oct 16, 4:42 PM ET). Rookie Jalon Daniels has been starting.
• Tampa Bay played Week 5 TNF, so it gets extra rest.
• Pittsburgh passes 66% of the time (2nd-highest). DK Metcalf has 37 targets, Jaylen Warren 26 and Roman Wilson 25.
• Tampa Bay's defense allows the 2nd-fewest rushing yards (75.8/g, 3.61 yds/carry) and 226.6 pass yds/g. Classic pass funnel.
• Tampa Bay's offense: Emeka Egbuka has 33 targets, Cade Otton 27 and Chris Godwin 21. Bucky Irving has 12 red-zone carries and 3 TDs.
• Pittsburgh's defense allows 6.53 net yds/dropback (11th-most) and has 11 sacks.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• TB (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: QB Baker Mayfield (right thumb), WR David Sills (hamstring) [FP/FP/FP; designation as posted by the club], S Antoine Winfield Jr. (rib). Doubtful: CB Benjamin Morrison (quad). Questionable: LB SirVocea Dennis (ankle/foot), CB Ayden Garnes (ankle), LB Josiah Trotter (knee), RB Sean Tucker (quad). No designation: OT Tristan Wirfs (knee) [FP/FP/FP]. (buccaneers.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• PIT (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: WR Roman Wilson (finger), WR Ben Skowronek (calf), S DeShon Elliott (knee). Questionable: WR DK Metcalf (illness), CB Jalen Ramsey (wrist), RB Rico Dowdle (toe), CB Jamel Dean (ankle), DT Keeanu Benton (ankle). No designation: LB T.J. Watt (rest, not injury related) [LP/FP/FP], DT Cameron Heyward (rest, not injury related) [DNP/FP/FP]. (steelers.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).

Prop markets worth researching

• PIT QB passing yards and Metcalf receiving yards: a pass-heavy offense against a defense built to stop the run.
• TB QB passing / rushing markets: who starts at QB is the whole story. Mayfield is listed Out on the Friday final report; rookie QB volume vs. a pressure defense.
• Egbuka / Otton receptions: the target leaders, whoever ends up throwing to them.
• PIT RB rushing yards (both directions): it runs straight into Tampa Bay's strength.

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Thursday night

G1 · Seahawks @ Broncos (Thursday Night Football) · Played Thu Oct 15 · Prime Video · Empower Field at Mile High, Denver

Injuries to watch: SEA@DEN final injury report and official inactives (TNF, played Thu Oct 15)

• SEA final report: Out: RB Zach Charbonnet (knee), LB Chazz Surratt (calf), LB Drake Thomas (ankle). No game designation: WR Jaxon Smith-Njigba (ankle; limited, limited, full Wed), QB Drew Lock (right forearm; limited all week), DT Leonard Williams (ankle; limited all week), RB George Holani (ribs, knee; full all week), WR Irvin Charles (knee; full Mon/Tue per seahawks.com) (seahawks.com Week 6 report + NFL.com Week 6 injury report, checked Oct 15, 4:46 PM ET).
• DEN final report: Out: CB Pat Surtain II (ankle), S Talanoa Hufanga (ankle). Questionable: CB Riley Moss (ribs; limited all week), now active per the official inactives below. No designation: DE Sai'vion Jones (shoulder), S Brandon Jones (foot), G Ben Powers (biceps) (denverbroncos.com Week 6 report + NFL.com, checked Oct 15, 4:46 PM ET).
• Official inactives (NFL.com Week 6 Thursday night inactives + denverbroncos.com, checked Oct 15, 6:56 PM ET): SEA: QB Jalen Milroe, RB Robert Henry Jr., WR Montorie Foster Jr., NT Brandon Pili, LB Chazz Surratt, LB Drake Thomas, CB Avery Smith. DEN: QB Sam Ehlinger (emergency third QB), TE Dallen Bentley, OL Kage Casey, DT Tyler Onyedim, DL Jordan Jackson, CB Patrick Surtain II, S Talanoa Hufanga. CB Riley Moss is active.

London, Sunday morning

G2 · Texans @ Jaguars · Sun Oct 18, 9:30 AM ET / 2:30 PM BST · NFL Network · Wembley Stadium, London, open-air · not in the 1 PM window

Matchup notes

• Jacksonville's defense allows the 3rd-most passing yards (266.2/g) and 7.04 net yds/dropback (6th-most), but the fewest rushing yards (64.4/g) and fewest yards per carry (3.04). Textbook pass funnel.
• Houston passes 63% of the time. Targets: Dalton Schultz 31, Xavier Hutchinson 31, Nico Collins 25 (249 yds). David Montgomery has 9 red-zone carries and 3 TDs.
• Houston's defense funnels the same way: 234 pass yds/g (10th-most), 78.8 rush yds/g (3rd-fewest) and 18 sacks.
• Jacksonville passes 53% of the time. Parker Washington has 35 targets (26% share); Brenton Strange has 26 and Jakobi Meyers 18.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 8:39 PM ET)

• HOU (Friday final report via NFL.com; houstontexans.com's table still had no Friday column or designations at 8:39 PM ET; NFL.com practice status in brackets for players with no designation): Out: RB David Montgomery (groin), S Jalen Pitre (shoulder), WR Tank Dell (knee). Questionable: CB Ja'Marcus Ingram (elbow), LB Henry To'oTo'o (shoulder). No designation: WR Nico Collins [limited], TE Dalton Schultz [limited], DE Will Anderson Jr. [limited] (NFL.com Week 6 injury report; checked Oct 16, 8:39 PM ET).
• JAX (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: CB Montaric Brown (hamstring), LS Ross Matiscik (shoulder). Questionable: CB Jaylon Jones (hamstring). No designation: TE Nate Boerkircher (back) [LP/LP/LP], CB Jarrian Jones (elbow) [LP/LP/FP], CB Jourdan Lewis (hamstring) [LP/LP/LP], S Eric Murray (concussion) [LP/LP/FP]. (jaguars.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).

Prop markets worth researching

• HOU passing yards and Schultz/Hutchinson/Collins receiving yards: you get the pass-funnel angle and the CB-injury angle in one.
• JAX passing yards and Parker Washington receptions: Houston's defense funnels the same direction.
• Sacks (both QBs): Houston leads its side in sacks.
• RB rushing yards (both teams, both directions): each back runs into a top-4 run defense by yards.

Sunday afternoon: the 4 PM ET games

G10 · Cardinals @ Rams · Sun 4:05 PM ET · FOX · SoFi Stadium, covered by a fixed translucent roof

Matchup notes

• Arizona runs a two-man target tree: Trey McBride 56 (29%) and Michael Wilson 51 (26%), with 11 and 9 red-zone targets. Rookie RB Jeremiyah Love has 11 red-zone carries.
• The Rams' defense allows the 2nd-fewest passing yards (156.8/g) and the 4th-fewest net yds/dropback (5.09).
• Arizona's defense allows the most net yds/dropback (7.89) and is tied for the most passing TDs allowed (14).
• The Rams pass 65% of the time, with the most pass attempts per game (45.2). Davante Adams has 45 targets and 441 yds, and Puka Nacua also has 45. Kyren Williams has 17 red-zone carries and 5 TDs.
• The Rams played Week 5 MNF (Mon Oct 12), so this is a normal 6-day turnaround.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 6:03 PM ET)

• ARI (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: RB Jeremiyah Love (ankle), S Wydett Williams Jr. (concussion), S Andrew Wingard (knee). Questionable: S Budda Baker (rest, not injury related/groin), S Kitan Crawford (ankle), OLB Zaven Collins (hip), P Blake Gillikin (back). No designation: WR Devin Duvernay (ribs) [LP/LP/LP], QB Carson Beck (back) [–/–/LP]. (azcardinals.com Week 6 final report via the official team-site injury feed; checked Oct 16, 6:03 PM ET).
• LA (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Questionable: S Kam Curl (ankle), CB Trent McDuffie (groin). No designation: WR Alex Bachman (wrist) [LP/FP/FP], TE Colby Parkinson (shoulder) [LP/LP/FP], TE Davis Allen (foot) [DNP/DNP/LP], TE Tyler Higbee (rest, not injury related) [–/–/DNP]. (therams.com Week 6 final report via the official team-site injury feed; checked Oct 16, 6:03 PM ET).

Prop markets worth researching

• LA passing yards / passing TDs and Adams/Nacua receiving yards: they face the most generous pass defense by efficiency.
• Kyren Williams anytime TD: if he's your anytime touchdown scorer research of the week, the case is a red-zone workload.
• McBride / Wilson receptions: concentrated volume against a stingy pass defense. Volume vs. efficiency, again.
• ARI RB rushing yards: Jeremiyah Love (ankle) is listed Out on Arizona's Friday final report, so check who gets the carries.

G11 · Chargers @ Chiefs · Sun 4:25 PM ET · CBS · Arrowhead, outdoors

Matchup notes

• Kansas City is coming off its Week 5 bye. Kenneth Walker III has 19 red-zone carries (8 inside the 5) and 6 TDs. Travis Kelce has 22 targets (246 yds), and Xavier Worthy has 22.
• Rashee Rice (hamstring/knee) is listed Out on Kansas City's Friday final report (chiefs.com, checked Fri Oct 16, 4:42 PM ET).
• The Chiefs' defense allows the 7th-fewest rushing yards (93/g).
• The Chargers spread the ball around: Tre' Harris 25 targets, Quentin Johnston 19, Ladd McConkey 17. Omarion Hampton has 14 red-zone carries and 3 TDs.
• The Chargers' defense has allowed 6.35 net yds/dropback (16th-most) and 7 rushing TDs (tied 3rd-most).

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 4:42 PM ET)

• LAC (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: OT Joe Alt (neck), G Kayode Awosika (fibula), WR Tre' Harris (hamstring), CB Donte Jackson (hamstring), S Derwin James Jr. (hamstring). Doubtful: CB Rodney Shelley (hamstring). Questionable: DL Jamaree Caldwell (knee), OLB Bud Dupree (neck), LB Daiyan Henley (knee), WR KeAndre Lambert-Smith (hamstring), WR Brenen Thompson (quadricep), DL Dalvin Tomlinson (hamstring). No designation: WR Quentin Johnston (chest) [LP/LP/FP], TE Charlie Kolar (forearm) [FP/FP/FP], OLB Khalil Mack (rest, not injury related) [DNP/FP/FP], WR Ladd McConkey (foot) [LP/LP/FP], WR Marquez Valdes-Scantling (rib) [LP/FP/FP]. (chargers.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).
• KC (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: WR Rashee Rice (hamstring/knee), OT Josh Simmons (back). Questionable: CB L'Jarius Sneed (knee). No designation: QB Patrick Mahomes (knee) [FP/FP/FP]. (chiefs.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).

Prop markets worth researching

• Walker rushing yards and anytime TD: the red-zone leader against a defense that has allowed rushing TDs.
• Kelce / Worthy receptions: Rashee Rice is listed Out on the Friday final report, which reshapes the target tree.
• LAC passing yards and WR receiving: Kansas City funnels away from the run. On the Friday final report Tre' Harris is Out, KeAndre Lambert-Smith and Brenen Thompson are Questionable, and McConkey and Johnston have no designation.

G12 · Bills @ Raiders · Sun 4:25 PM ET · CBS · Allegiant Stadium, fixed dome

Matchup notes

• Josh Allen leads Buffalo with 8 TDs on 13 red-zone carries (7 inside the 5). Yes, the quarterback. That makes him a real anytime touchdown scorer market here, not a novelty. James Cook III has 18 red-zone carries. Dalton Kincaid has 277 receiving yds.
• The Raiders' defense allows 141.6 rush yds/g (5th-most) and 5.4 yds/carry (2nd-most).
• Buffalo's defense allows 280.4 pass yds/g (2nd-most) and has allowed 13 passing TDs.
• Las Vegas spreads its targets around: Brock Bowers 34, Ashton Jeanty 30, Michael Mayer 25. Jeanty also has 16 red-zone carries and 6 red-zone targets.
• Buffalo played Week 5 MNF at the Rams, then travels LA → Las Vegas on a 6-day turnaround.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 8:39 PM ET)

• BUF (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Questionable: CB Dee Alford (ankle), WR DJ Moore (shoulder), DL Ed Oliver (knee), WR Josh Palmer (shoulder), DL T.J. Sanders (shoulder). No designation: CB Christian Benford [FP/FP/FP], WR Keon Coleman [FP/FP/FP], RB Ty Johnson [LP/LP/FP]. (buffalobills.com Week 6 final report via the official team-site injury feed; checked Oct 16, 8:39 PM ET).
• LV (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: DT Tonka Hemingway (concussion), TE Carter Runyon (foot), WR Dont'e Thornton Jr. (hamstring) [FP/FP/FP; designation as posted by the club]. Questionable: G Trey Zuhn III (knee). No designation: TE Brock Bowers (knee) [LP/FP/FP], RB Ashton Jeanty (foot) [FP/FP/FP], WR Jalen Nailor (concussion) [DNP/LP/FP], WR Dareke Young (shoulder) [FP/FP/FP]. (raiders.com Week 6 final report via the official team-site injury feed; checked Oct 16, 8:39 PM ET).

Prop markets worth researching

• Allen rushing yards and anytime TD: QB goal-line usage.
• Cook rushing yards: Vegas allows yards per carry.
• Bowers / Mayer receiving yards: Buffalo allows passing yards and TDs.
• Jeanty rushing + receiving yards: Ashton Jeanty has no game designation on the Friday final report (FP/FP/FP).

Sunday night

Sunday Night Football player props: G13 · Cowboys @ Packers · Sun 8:20 PM ET · NBC · Lambeau Field, outdoors

Matchup notes

• Dallas played Week 5 TNF, so it gets extra rest. CeeDee Lamb has 51 targets (27% share, 507 yds). George Pickens has 41 targets.
• Javonte Williams has 21 red-zone carries, 13 inside the 5, and 7 TDs. Nobody in our sample has more carries inside the 5; he's tied for the most.
• Green Bay's defense allows 128.6 rush yds/g (7th-most) and 8 rushing TDs (2nd-most), but the 5th-fewest passing yards (181/g).
• Green Bay throws more than anyone: the highest pass rate in the league (67%). Targets: Matthew Golden 44, Christian Watson 40 (474 yds, 7 red-zone targets, 6 TDs), Tucker Kraft 29.
• Dallas's defense allows the most rushing yards (169.8/g) and the 2nd-most net yds/dropback (7.83), and has given up 10 passing TDs.

Injuries to watch: Friday final reports with game designations (checked Fri Oct 16, 8:39 PM ET)

• DAL (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: CB Cobie Durant (hamstring), OT Drew Shelton (hamstring). Questionable: LB DeMarvion Overshown (hamstring), CB Joey Porter Jr. (ankle), CB Ameer Speed (knee). No designation: WR CeeDee Lamb (thigh) [FP/FP/FP], OLB Von Miller (rest, not injury related) [DNP; no Thursday or Friday entry on the club report]. NFL.com also lists DT LT Overton (foot) Questionable (DNP on NFL.com); he is not on dallascowboys.com's table (dallascowboys.com Week 6 final report via the official team-site injury feed + NFL.com Week 6 injury report; checked Oct 16, 8:39 PM ET).
• GB (Friday final report; practice Wed/Thu/Fri in brackets for players with no designation): Out: DT Jonathan Ford (calf), DT Javon Hargrave (Achilles), WR Skyy Moore (ankle), CB Benjamin St-Juste (hamstring). Doubtful: DT Jordon Riley (Achilles). Questionable: G Aaron Banks (knee/toe), DT Anthony Campbell (ankle), CB Brandon Cisse (hip), C/G Jacob Monk (quadricep), WR Savion Williams (ankle). No designation: CB Keisean Nixon (groin) [DNP/LP/LP]. (packers.com Week 6 final report via the official team-site injury feed; checked Oct 16, 4:42 PM ET).

Prop markets worth researching

• Javonte Williams rushing yards and anytime TD: tied for the top goal-line workload against a defense that allows rushing TDs.
• Lamb receptions / receiving yards: a high target share against a pass defense that allows few yards.
• GB passing yards / passing TDs and Watson anytime TD: Dallas allows both.
• GB RB rushing yards: by yards, Dallas has the most generous run defense.

Monday night

Best NFL player props for MNF: G14 · Commanders @ 49ers · Mon Oct 19, 8:15 PM ET · Levi's Stadium, outdoors

Matchup notes

• WAS and SF: Thursday practice reports are out (see Injuries below); final designations PENDING (Sat Oct 17). No game status yet (checked Fri Oct 16, 4:42 PM ET).
• Washington targets: Diggs 31, McLaurin 26, Antonio Williams 22.
• The 49ers' defense allows the 6th-fewest net yds/dropback (5.39) and 97.8 rush yds/g.
• Washington's defense is tied for the most passing TDs allowed (14) and gives up 255 pass yds/g (4th-most).
• San Francisco: Christian McCaffrey has 14 red-zone carries (8 inside the 5) and 5 TDs. George Kittle has 6 red-zone targets and 4 TDs. Mike Evans has 34 targets.

Injuries to watch: Monday game. Practice reports only; final designations PENDING (Sat Oct 17)

• WAS and SF play Monday. These are practice lines only; final designations PENDING (Sat Oct 17). Friday practice columns were still blank on 49ers.com and NFL.com as of Oct 16, 4:42 PM ET.
• SF (Thursday practice, first Week 6 report; final designations PENDING, Sat Oct 17): RB Christian McCaffrey (not injury related, resting player) DNP; WR Mike Evans (ribs, Achilles) DNP; WR Deebo Samuel Sr. (hamstring) DNP; DL Nick Bosa (knee, calf) DNP; WR Christian Kirk (calf) and FB Kyle Juszczyk (knee) limited; WR Jacob Cowing (ankle) full (49ers.com Week 6 report via the official team-site injury feed; checked Oct 16, 9:30 AM ET). NFL.com also lists T Trent Williams DNP (not on the 49ers.com table; NFL.com Week 6 injury report, checked Oct 16, 9:30 AM ET).
• WAS (Thursday practice, first Week 6 report; final designations PENDING, Sat Oct 17): QB Jayden Daniels full; WR Terry McLaurin and RB Austin Ekeler limited; WR Stefon Diggs, RB Jacory Croskey-Merritt and QB Marcus Mariota DNP. Body parts not listed (Washington's Week 6 report, posted as a joint Commanders–49ers table on commanders.com and 49ers.com, Thursday column, + NFL.com Week 6 injury report, which match; checked Fri Oct 16, 4:42 PM ET).

Prop markets worth researching

• SF passing TDs and Kittle anytime TD: Washington allows passing TDs, which is where any anytime touchdown scorer research on George Kittle starts.
• McCaffrey rushing + receiving yards and anytime TD: work inside the 5.
• Daniels rushing yards: QB rushing against an efficient pass defense.
• WAS WR receptions: Diggs and McLaurin lead the targets. Check Saturday's final report.

Injury watch: Week 6 injury reports

Status note: every injury line on this page comes from the Week 6 official injury reports. Friday final reports with game designations are in for all 24 Sunday teams (last checked Fri Oct 16, 8:39 PM ET); Houston and New Orleans are from NFL.com because their club tables had no Friday column. SEA@DEN (played Thu Oct 15) shows its final report and the official inactives, checked Thu Oct 15, 6:56 PM ET. Washington and San Francisco show practice lines only; their final designations come Sat Oct 17. Statuses can still change before each kickoff, so check any list of the best NFL player prop bets for Week 6 against these final reports.

The names most likely to move things:

• Lamar Jackson (G4)
• Saquon Barkley (G8)
• Jalen Hurts (G8; listed Out on Philadelphia's Friday final report)
• Baker Mayfield and the TB QB spot (G9)
• Ashton Jeanty (G12)
• CeeDee Lamb (G13)
• Breece Hall (G6)
• Rashee Rice (G11)
• Washington and San Francisco (G14; first Week 6 practice reports out; final Sat Oct 17)
• Caleb Williams (G3)

Friday final reports are in for all Sunday games, and Washington and San Francisco get their final designations on Saturday Oct 17.

Before the early games

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Our graded record so far

See the graded record on the Desk Record. Curious how a pick gets graded? Here's how we grade.

FAQ

When are the NFL Week 6 games in 2026?

Week 6 opened with Seahawks at Broncos on Thursday, October 15 at 8:15 PM ET, and ends with Commanders at 49ers on Monday, October 19 at 8:15 PM ET. Sunday, October 18 has a 9:30 AM ET London game (Texans at Jaguars), seven 1:00 PM ET games, three late-afternoon games and Cowboys at Packers on Sunday night. The Bengals, Lions, Dolphins and Vikings are on bye.

Which Week 6 games are in the Sunday 1 PM ET window?

Seven games kick off at 1:00 PM ET on Sunday, October 18: Bears at Falcons, Ravens at Browns, Titans at Colts, Jets at Patriots, Saints at Giants, Panthers at Eagles and Steelers at Buccaneers. The Desk's research for these games is at centerpointsports.com before kickoff.

What does an anytime touchdown scorer bet mean?

An anytime touchdown (anytime TD) prop pays if the named player scores a touchdown at any point in the game, including overtime at most sportsbooks. Rushing, receiving and return touchdowns count. Rules on overtime, defensive scores and players who don't take the field vary by sportsbook, so check your book's house rules.

Does a quarterback's passing touchdown count for an anytime TD prop?

No. A passing touchdown counts for the receiver who scores, not the quarterback. A quarterback's anytime TD prop only pays if he rushes or catches the ball into the end zone himself.

What should I look at for Week 6 anytime touchdown markets?

Start with who gets the ball near the goal line: red-zone carries, carries inside the 5-yard line and red-zone targets. Then check the official injury reports on Friday, and compare the price for the same player across sportsbooks, because they often differ. Red-zone usage is research, not a prediction. No pick is guaranteed.

When are Week 6 player props posted?

Sportsbooks usually open player props during the week and add or adjust markets as injury news comes in. Many markets aren't final until official inactives are announced about 90 minutes before kickoff. Prices change, so check them again close to game time.

How do I get the Desk's Week 6 research?

Start at centerpointsports.com for the Desk's game research and matchup breakdowns before the early games. PRO is $19.99 for 7 days, $49.99 for 30 days or $199 for the season. For adults 21 and older. No pick is guaranteed.

Do NFL prop picks always win?

No. Every NFL prop can lose, and injuries and late news can change a game. Only bet what you can afford to lose. Research tools. We don't set odds or take bets. No pick is guaranteed. 21+. Gambling problem? Please call 1-800-GAMBLER for help. Part of our mission is helping people who struggle get support.

Sources

Schedule, venue, weather and roster sources checked Fri Oct 9, 2026 (ET); rosters re-checked Thu Oct 15, 2026 (ET). Injury reports and stats show their own check times below. SEA@DEN inactives were checked Thu Oct 15, 6:56 PM ET. Friday final reports for the Sunday games were checked Fri Oct 16, 4:42 PM, 6:03 PM and 8:39 PM ET; Washington and San Francisco get re-verified on Saturday Oct 17.

Schedule and venue

• NFL.com Week 6 schedule (primary), checked ~12:57 PM ET.
• London game (Texans @ Jaguars, Wembley Stadium, Sun Oct 18, 9:30 AM ET / 2:30 PM BST):
  • houstontexans.com: https://www.houstontexans.com/news/texans-jaguars-london-2026
  • jaguars.com game page: https://www.jaguars.com/game-day/2026/reg-week6/texans-at-jaguars/box-score
  • NFL.com game center: https://www.nfl.com/games/texans-at-jaguars-2026-reg-6

Weather (London)

• Met Office, Wembley (Greater London) forecast: https://weather.metoffice.gov.uk/forecast/gcpv307jh. Provisional until the final days before kickoff.

Rosters

• NFL.com player pages: https://www.nfl.com/players/kenneth-walker-iii/, https://www.nfl.com/players/dk-metcalf/, https://www.nfl.com/players/mike-evans/, https://www.nfl.com/players/jaylen-waddle/, https://www.nfl.com/players/david-montgomery/
• Official team roster pages (/team/players-roster/) for all 28 Week 6 teams, including https://www.seahawks.com/team/players-roster/, https://www.dallascowboys.com/team/players-roster/, https://www.baltimoreravens.com/team/players-roster/, https://www.clevelandbrowns.com/team/players-roster/, https://www.patriots.com/team/players-roster/, https://www.philadelphiaeagles.com/team/players-roster/, https://www.commanders.com/team/players-roster/ and https://www.chiefs.com/team/players-roster/

Injuries and news

• NFL.com Week 6 injury report and the official team-site Week 6 injury reports, checked Thu Oct 15, 4:46 PM ET and Fri Oct 16, 9:30 AM ET; Friday final reports checked Fri Oct 16, 4:42 PM, 6:03 PM and 8:39 PM ET.
• SEA@DEN final report via seahawks.com/denverbroncos.com.

Stats

• nflverse play-by-play 2026 (CC-BY 4.0). Last modified Tue Oct 13, 8:55 AM ET; 79 games through Week 5, Monday night included.

Play-by-play data: nflverse (CC-BY 4.0). Schedule: NFL.com. Injury statuses: official NFL team injury reports.

PRO plans: centerpointsports.com/#join.

Research tools. We don't set odds or take bets. No pick is guaranteed. 21+. Gambling problem? Please call 1-800-GAMBLER for help. Part of our mission is helping people who struggle get support.

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